Leptin Podcast + Transcript

Podcast Link: https://soundcloud.com/robert-stoddard-3/leptin-podcast


Manuscript:

Hello, I am Bob Stoddard and this is a podcast about the
hormone in your body, leptin.  Leptin is a hormone that
tells the body when it is full or had enough to eat.  This
is the opposing hormone to ghrelin; which tells the body
when it is hungry or needs to eat.  When a person has more
ghrelin and not enough leptin in their system they continue
to eat. This is a common cause of obesity. Leptin is mainly
produced in the adipocytes or fat cells. The amount of
leptin your body produces is regulated by the amount of
energy stored in the fat cells.  If the body has enough
energy stored it sends signals via the endocrine system to
the brain.  This creates a negative feedback loop that
reduces your appetite until your body needs more energy.  At
this point leptin production will continue. Leptin is water
soluble so that it can pass through the cell membrane. It
then travels to the brain. The leptin produced activates a
receptor mainly located in the hypothalamus.  When the
receptor is active, you lose appetite until the weight and
energy you gained is expended.